Many, if not most scopes are going to be more precise within the range where the reticle centered in the scope. Having a 20 MOA base will almost demand that out to quite long range accuracy will suffer. If I was doing most of my shooting between 100 - 600 yards I would like my scope to perform at it's maximum within that range.
However if I was shooting primarily 400 - 1,000+ I might go with such a base.
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